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Pregled bibliografske jedinice broj: 46051

Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia


Pejša, Vlatko; Stančić, Vladimir; Petrovečki, Mladen; Lang, Nada; Stanović, Silvana; Kardum, Ika; Boranić, Milivoj
Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia // Molecular Oncology Today - Proceedings of the Croatian-Slovenian Meeting / Osmak, Maja ; Škrk, Janez (ur.).
Zagreb: Hrvatska liga protiv raka, 1996. str. 131-135 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)


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Naslov
Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia

Autori
Pejša, Vlatko ; Stančić, Vladimir ; Petrovečki, Mladen ; Lang, Nada ; Stanović, Silvana ; Kardum, Ika ; Boranić, Milivoj

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Molecular Oncology Today - Proceedings of the Croatian-Slovenian Meeting / Osmak, Maja ; Škrk, Janez - Zagreb : Hrvatska liga protiv raka, 1996, 131-135

Skup
Molecular Oncology Today, Croatian-Slovenian Meeting

Mjesto i datum
Zagreb, Hrvatska, 19, 12.1995

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
chronic lymphocytic leukemia; cultured bone marrow cells; GM-CFU assay; hemopoietic inhibitory factors

Sažetak
This work was aimed at assessing the prognostic value of the colony-forming ability in vitro (the GM-CFU assay) of the bone marrow cells collected at diagnosis from 13 patients with untreated chronic lymphocytic leukemia (CLL). The GM-CFU count per 10E5 cellswas reduced in proportion to the total tumor mass (TTM score) and to the clinico-pathological staging of the disease according to the Rai criteria. A few discordant examples of low GM-CFU counts in early stages of the disease might be considered an unfavourable prognostic sign. The reduction of the bone marrow progenitor (colony-forming) cell compartment was interpreted as indicating an impairment of normal hematopoiesis by inhibitory factor(s) released from the CLL cells.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
00981106

Ustanove:
Institut "Ruđer Bošković", Zagreb


Citiraj ovu publikaciju:

Pejša, Vlatko; Stančić, Vladimir; Petrovečki, Mladen; Lang, Nada; Stanović, Silvana; Kardum, Ika; Boranić, Milivoj
Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia // Molecular Oncology Today - Proceedings of the Croatian-Slovenian Meeting / Osmak, Maja ; Škrk, Janez (ur.).
Zagreb: Hrvatska liga protiv raka, 1996. str. 131-135 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
Pejša, V., Stančić, V., Petrovečki, M., Lang, N., Stanović, S., Kardum, I. & Boranić, M. (1996) Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia. U: Osmak, M. & Škrk, J. (ur.)Molecular Oncology Today - Proceedings of the Croatian-Slovenian Meeting.
@article{article, year = {1996}, pages = {131-135}, keywords = {chronic lymphocytic leukemia, cultured bone marrow cells, GM-CFU assay, hemopoietic inhibitory factors}, title = {Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia}, keyword = {chronic lymphocytic leukemia, cultured bone marrow cells, GM-CFU assay, hemopoietic inhibitory factors}, publisher = {Hrvatska liga protiv raka}, publisherplace = {Zagreb, Hrvatska} }
@article{article, year = {1996}, pages = {131-135}, keywords = {chronic lymphocytic leukemia, cultured bone marrow cells, GM-CFU assay, hemopoietic inhibitory factors}, title = {Clonal cultures of bone marrow cells of the patients with chronic lymphocytic leukemia}, keyword = {chronic lymphocytic leukemia, cultured bone marrow cells, GM-CFU assay, hemopoietic inhibitory factors}, publisher = {Hrvatska liga protiv raka}, publisherplace = {Zagreb, Hrvatska} }




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