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Pregled bibliografske jedinice broj: 459966

Botulinum toxin A injection for primary and recurrent chalazia


Knežević, Tamara; Iveković, Renata; Astalos Pavičić, Jasna; Novak Lauš, Katia; Mandić, Zdravko; Matejčić, Aljoša
Botulinum toxin A injection for primary and recurrent chalazia // Graefe's archive for clinical and experimental ophthalmology, 247 (2009), 6; 789-794 doi:10.1007/s00417-008-0992-3 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 459966 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Botulinum toxin A injection for primary and recurrent chalazia

Autori
Knežević, Tamara ; Iveković, Renata ; Astalos Pavičić, Jasna ; Novak Lauš, Katia ; Mandić, Zdravko ; Matejčić, Aljoša

Izvornik
Graefe's archive for clinical and experimental ophthalmology (0721-832X) 247 (2009), 6; 789-794

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
btulinum toxin A; chalazia

Sažetak
To study the efficacy and safety of subcutaneous botulinum toxin A injections in the treatment of primary and recurrent chalazia. Prospective, placebo-controlled consecutive case-series trial. Sixty three patients were divided into two groups: group 1 consisting of 32 patients previously diagnosed with and treated for primary or recurrent chalazia with 2-5 international units (IU) in 0.2-0.5 ml of preserved saline solution of botulinum toxin injection, and group 2 consisting of 31 patients receiving placebo. The main outcome measures were localization and duration of the disease, size of chalazion before and after treatment, clinical resolution of chalazion, time to resolution, and complications of treatment. There was a clinically and statistically significant between-group difference in the rate of therapeutic success and post-therapeutic chalazion regression, but not in the rate of complications. Botulinum toxin A injection is effective and safe treatment for primary and recurrent chalazia. Lesion regression that did not respond to the average of two injections would benefit more from surgical excision or systemic antibiotic therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080134-0121 - Percepcija i prevencija čimbenika rizika za aterosklerozu u Hrvatskoj (Reiner, Željko, MZOS ) ( POIROT)
134-1340236-0181 - Distiroidna orbitopatija i glaukom (Iveković, Renata, MZOS ) ( POIROT)
134-1340236-0185 - Rano otkrivanje primarnog glaukoma otvorenog kuta (Novak-Lauš, Katia, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Citiraj ovu publikaciju

Knežević, Tamara; Iveković, Renata; Astalos Pavičić, Jasna; Novak Lauš, Katia; Mandić, Zdravko; Matejčić, Aljoša
Botulinum toxin A injection for primary and recurrent chalazia // Graefe's archive for clinical and experimental ophthalmology, 247 (2009), 6; 789-794 doi:10.1007/s00417-008-0992-3 (međunarodna recenzija, članak, znanstveni)
Knežević, T., Iveković, R., Astalos Pavičić, J., Novak Lauš, K., Mandić, Z. & Matejčić, A. (2009) Botulinum toxin A injection for primary and recurrent chalazia. Graefe's archive for clinical and experimental ophthalmology, 247 (6), 789-794 doi:10.1007/s00417-008-0992-3.
@article{article, year = {2009}, pages = {789-794}, DOI = {10.1007/s00417-008-0992-3}, keywords = {btulinum toxin A, chalazia}, journal = {Graefe's archive for clinical and experimental ophthalmology}, doi = {10.1007/s00417-008-0992-3}, volume = {247}, number = {6}, issn = {0721-832X}, title = {Botulinum toxin A injection for primary and recurrent chalazia}, keyword = {btulinum toxin A, chalazia} }
@article{article, year = {2009}, pages = {789-794}, DOI = {10.1007/s00417-008-0992-3}, keywords = {btulinum toxin A, chalazia}, journal = {Graefe's archive for clinical and experimental ophthalmology}, doi = {10.1007/s00417-008-0992-3}, volume = {247}, number = {6}, issn = {0721-832X}, title = {Botulinum toxin A injection for primary and recurrent chalazia}, keyword = {btulinum toxin A, chalazia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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