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Pregled bibliografske jedinice broj: 459171

5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder


Hranilović, Dubravka; Blažević, Sofia; Babić, Marina; Šmurinić, Maja; Bujas-Petković, Zorana; Jernej, Branimir
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder // Psychiatry research, 178 (2010), 3; 556-558 doi:10.1016/j.psychres.2010.04.007 (međunarodna recenzija, članak, znanstveni)


Naslov
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder

Autori
Hranilović, Dubravka ; Blažević, Sofia ; Babić, Marina ; Šmurinić, Maja ; Bujas-Petković, Zorana ; Jernej, Branimir

Izvornik
Psychiatry research (0165-1781) 178 (2010), 3; 556-558

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Serotonin ; -1438 A/G ; His452Tyr

Sažetak
Disturbances in expression/function of 5-HT2A receptor are implicated in autism. Association of 5-HT2A receptor gene with autism was studied in Croatian population. Distribution frequencies for alleles, genotypes and haplotypes of -1438 A/G and His452Tyr polymorphisms were compared in samples of 103 autistic and 214 control subjects. Significant overrepresentation of G allele and GG genotype of -1438 A/G polymorphism was observed in group of autistic subjects, supporting possible involvement of 5-HT2A receptor in development of autism.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-1081870-2395 - Serotonergična neurotransmisija: geni, proteini i ponašanje (Jasminka Štefulj, )
119-1081870-2396 - Neurobiološka podloga autizma: uloga serotoninskog sustava (Dubravka Hranilović, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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