engleski

Genetic polymorphisms of thiopurine methyltransferase in Croatian inflammatory bowel disease patients

TPMT*3C was the most frequently occuring nonfunctional TPMT allele in Croatian IBD population. Although predominant allele is obvious in this set of patients, regarding to relatively lower frequency of TPMT polymorphisms we need further investigation in cohort of healthy controls prior definite conclusion about benefit of pharmacogenetically guided dosing in our population.

genetic polymorphism; thiopurine methyltransferase; Croatian IBD patients

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