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Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide


Štefulj, Jasminka; Mokrović, Gordana; Hranilović, Dubravka; Bordukalo-Nikšić, Tatjana; Bakula, Mirko; Kubat, Milovan; Jernej, Branimir
Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide // Psychiatry research, 186 (2011), 2/3; 446-447 doi:10.1016/j.psychres.2010.08.034 (međunarodna recenzija, članak, znanstveni)


Naslov
Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide

Autori
Štefulj, Jasminka ; Mokrović, Gordana ; Hranilović, Dubravka ; Bordukalo-Nikšić, Tatjana ; Bakula, Mirko ; Kubat, Milovan ; Jernej, Branimir

Izvornik
Psychiatry research (0165-1781) 186 (2011), 2/3; 446-447

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Suicide ; Tph2 ; association study

Sažetak
The association between suicide and G-703T polymorphism of the tryptophan hydroxylase 2 (Tph2), the rate-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was studied in a sample of 291 suicide victims and 280 healthy subjects of Croatian origin. No significant differences were found between the groups. Obtained results do not support involvement of the investigated polymorphism in the susceptibility to suicide completion.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-1081870-2395 - Serotonergična neurotransmisija: geni, proteini i ponašanje (Jasminka Štefulj, )
119-1081870-2396 - Neurobiološka podloga autizma: uloga serotoninskog sustava (Dubravka Hranilović, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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