engleski

Are Lipoprotein Disturbances in Chronic Hemodialyzed Patients Only Renal Failure Related?

Chronically hemodialyzed (HD) patients frequently suffer from quantitative and even more often qualitative serum lipids disorders. Mostly they have increased triglycerides and VLDL-cholesterol, slightly increased or normal total and LDL-cholesterol and decreased HDL-cholesterol concentrations. The study compared lipid profile between two groups of chronic HD patients coming from regionally distinct areas , the continental and the maritime one. The aim was to examine the hypothetic influence of their different dietary habits on lipide profile. The study included 72 patients from continental region (39 men) and 50 from maritime part of the country (30 men). Patients suffering from diabetes mellitus, hypothyroidism, liver disease, alcoholics as well as sevelamer treated patients were not included. Prior to a HD session the patients were determined fasting total cholesterol, triglycerides, HDL-and LDL-cholesterol, total proteins, albumins and C-reactive protein serum concentrations. All patients were undergoing bicarbonate hemodialysis with polysulphone dialysers of low permeability. The continental group of patients were somewhat older, undergoing HD for longer period of time, of lower height, greater weight, greater body mass index, higher total (4.70±0.91: 4.42±1.02 mmol/L), and LDL-cholesterol (2.78±0.74:2.66±0.75 mmol/L) concentrations, while lower triglycerides (1.72±0.84:1.81±0.83 mmol/L) and HDL-cholesterol (1.13±0.42:1.16±0.54 mmol/L). However, all the differences were without statistical significance.

plasmatic lipoproteins; cholesterol; triglycerides; hemodialysis; dietary habits

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