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Pregled bibliografske jedinice broj: 45012

Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia


Rudan, Igor; Rudan, Pavao
Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia // Human Population Genetics in Europe / Sussanne, Charles ; Bodzsar, Eva B. (ur.).
Budapest: Eotvos University Press, 2000. str. 117-128


Naslov
Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia

Autori
Rudan, Igor ; Rudan, Pavao

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Human Population Genetics in Europe

Urednik/ci
Sussanne, Charles ; Bodzsar, Eva B.

Izdavač
Eotvos University Press

Grad
Budapest

Godina
2000

Raspon stranica
117-128

ISBN
963-9316-12-1

Ključne riječi
Inbreeding coefficients, autosomal genetic polymorphisms, isonymy, population genetics, anthropology

Sažetak
The aim of this study was to compare the values of the coefficient of inbreeding determinated from isonymy data and the one determinated from deviation from Hardy-Weinberg expectations in phenotype (and genotype) frequencies of heterozygotes for codominant, biallelic autosomal genetic polymorphisms, in this case erythrocyte antigens of MN-system, S-system and Kell-system. The study was performed in a sample of Hvar island population, presumed to be highly inbred. The study involved a total of 593 marital pairs (1186 individuals) and a blood sample was collected from 968 of them (81, 6%). The value of inbreeding coefficient determinated from MN-system was 32, 2%, S-system 2, 6%, Kell system 13, 1% and from isonymy 2, 3%. The reasons for the underestimation of the inbreeding coefficient from isonymy data in subdivided populations are discussed, with special consideration to factors affecting effective size, Wahlund’d principle, visible or invisible barriers to panmyxia, and “surname drift” over long time period.

Izvorni jezik
Engleski

Znanstvena područja
Etnologija i antropologija



POVEZANOST RADA


Projekt / tema
01960101

Ustanove
Institut za antropologiju

Autor s matičnim brojem:
Pavao Rudan, (41641)
Igor Rudan, (215633)

Citiraj ovu publikaciju

Rudan, Igor; Rudan, Pavao
Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia // Human Population Genetics in Europe / Sussanne, Charles ; Bodzsar, Eva B. (ur.).
Budapest: Eotvos University Press, 2000. str. 117-128
Rudan, I. & Rudan, P. (2000) Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia. U: Sussanne, C. & Bodzsar, E. (ur.) Human Population Genetics in Europe. Budapest, Eotvos University Press, str. 117-128.
@inbook{inbook, year = {2000}, pages = {117-128}, keywords = {inbreeding coefficients, autosomal genetic polymorphisms, isonymy, population genetics, anthropology}, isbn = {963-9316-12-1}, title = {Comparison between Coefficients of Inbreeding Computed from Deficit of Heterozygotes for Codominant Autosomal Genetic Polymorphisms and from Isonymy data: A Study of Hvar Island Isolates, Croatia}, keyword = {inbreeding coefficients, autosomal genetic polymorphisms, isonymy, population genetics, anthropology}, publisher = {Eotvos University Press}, publisherplace = {Budapest} }