engleski

Sequence analysis of both genome segments of three Croatian infectious bursal disease field viruses

In order to determine mutations responsible for virulence, three Croatian field infectious bursal disease viruses (IBDV), designated Cro-Ig/02, Cro-Po/00 and Cro-Pa/98, were characterized. Full length genomic analysis of IBDV at both the nucleotide and amino acid level is necessary for accurate typing of isolates. That kind of analysis of Croatian IBDV isolates did not indicate that these strains have new antigenic or virulent features. But, by analyzing a larger and larger number of IBDV isolates worldwide, it would be possible to obtain better knowledge of mutations characteristic for virulence and pathogenicity and be able to assume the further evolution of the virus.

Croatia; field viruses; infectious bursal disease virus; sequence analysis; virulence

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