engleski

Genetic and cultural variability and goitre prevalence in Dogon population

The Dogon population living in the Sanga region, Republic of Mali, was investigated using demographic, migration, linguistic, anthropometric and genetic data on 7 subpopulation (village) groups. Although the Dogon population has been considered as culturally and ecologically homogenous the analysis shows considerable demographic and linguistic divergence between subdivisions. The inter-village migration analysis, which reveals limited gene flow, high endogamy and inbreeding values as well as distribution of some genetic frequencies and anthropometric markers show a marked microdifferentiation of the villages in this small geographic area. The analysis of endemic goitre carried out in the same population shows the prevalence of 52.6%. As the differences in prevalence of this disease reflect the observed genetic, anthropometric and cultural microdifferentiation, the findings are analyzed in the light of possible genetic predisposition to the disease.

goitre; genetics; anthropometry; variability; anthropology

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