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Pregled bibliografske jedinice broj: 440668

The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium

Tumir, Lidija-Marija; Grabar, Marina; Tomić, Sanja; Piantanida, Ivo
The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium // Tetrahedron, 66 (2010), 13; 2501-2513 doi:10.1016/j.tet.2010.01.063 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 440668 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium

Autori
Tumir, Lidija-Marija ; Grabar, Marina ; Tomić, Sanja ; Piantanida, Ivo

Izvornik
Tetrahedron (0040-4020) 66 (2010), 13; 2501-2513

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
nucleotide ; bis-phenanthridine ; recognition ; spectroscopy

Sažetak
Among series of novel bis-phenanthridinium – nucleobase conjugates, the adenine derivative revealed high (logKs = 6.9 M-1) and selective affinity toward complementary nucleotide (UMP), accompanied by specific change in the UV/Vis spectrum of phenanthridine subunits, differing significantly from changes caused by addition of other nucleotides. High stability and selectivity of adenine-conjugate/UMP non-covalent complex is, according to the molecular modelling studies, correlated to the number of inter- and intramolecular aromatic stacking interactions between phenanthridinium subunits, covalently attached adenine and added UMP, while the selectivity of adenine-conjugate toward UMP in respect to other nucleotides is most likely the consequence of additional hydrogen bonding between UMP and adenine.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija



POVEZANOST RADA

Projekti:
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Piantanida, Ivo, MZOS ) ( CroRIS)
098-1191344-2860 - Proučavanje biomakromolekula računalnim metodama i razvoj novih algoritama (Tomić, Sanja, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Lidija-Marija Tumir (autor)

Avatar Url Ivo Piantanida (autor)

Avatar Url Sanja Tomić (autor)

Avatar Url Marina Grabar Branilović (autor)

Poveznice na cjeloviti tekst rada:

doi fulir.irb.hr www.sciencedirect.com doi.org

Citiraj ovu publikaciju:

Tumir, Lidija-Marija; Grabar, Marina; Tomić, Sanja; Piantanida, Ivo
The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium // Tetrahedron, 66 (2010), 13; 2501-2513 doi:10.1016/j.tet.2010.01.063 (međunarodna recenzija, članak, znanstveni)
Tumir, L., Grabar, M., Tomić, S. & Piantanida, I. (2010) The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium. Tetrahedron, 66 (13), 2501-2513 doi:10.1016/j.tet.2010.01.063.
@article{article, author = {Tumir, Lidija-Marija and Grabar, Marina and Tomi\'{c}, Sanja and Piantanida, Ivo}, year = {2010}, pages = {2501-2513}, DOI = {10.1016/j.tet.2010.01.063}, keywords = {nucleotide, bis-phenanthridine, recognition, spectroscopy}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2010.01.063}, volume = {66}, number = {13}, issn = {0040-4020}, title = {The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium}, keyword = {nucleotide, bis-phenanthridine, recognition, spectroscopy} }
@article{article, author = {Tumir, Lidija-Marija and Grabar, Marina and Tomi\'{c}, Sanja and Piantanida, Ivo}, year = {2010}, pages = {2501-2513}, DOI = {10.1016/j.tet.2010.01.063}, keywords = {nucleotide, bis-phenanthridine, recognition, spectroscopy}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2010.01.063}, volume = {66}, number = {13}, issn = {0040-4020}, title = {The interactions of bis-phenanthridinium – nucleobase conjugates with nucleotides: adenine conjugate recognizes UMP in aqueous medium}, keyword = {nucleotide, bis-phenanthridine, recognition, spectroscopy} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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  • CA Search (Chemical Abstracts)

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