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Pregled bibliografske jedinice broj: 439419

GORBI: Web application for the prediction of a protein's functional context


Supek, Fran; Šmuc, Tomislav; Repar, Jelena; Škunca, Nives
GORBI: Web application for the prediction of a protein's functional context // The 3rd Adriatic Meeting on Computational Solutions in the Life Sciences - Book of Abstracts / Babić, Darko ; Došlić, Nađa ; Smith, David ; Tomić, Sanja ; Vlahoviček, Kristian (ur.).
Zagreb: Centre for Computational Solutions in the Life Sciences, 2009. str. 76-76 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 439419 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
GORBI: Web application for the prediction of a protein's functional context

Autori
Supek, Fran ; Šmuc, Tomislav ; Repar, Jelena ; Škunca, Nives

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
The 3rd Adriatic Meeting on Computational Solutions in the Life Sciences - Book of Abstracts / Babić, Darko ; Došlić, Nađa ; Smith, David ; Tomić, Sanja ; Vlahoviček, Kristian - Zagreb : Centre for Computational Solutions in the Life Sciences, 2009, 76-76

ISBN
978-953-6690-80-0

Skup
The 3rd Adriatic Meeting on Computational Solutions in the Life Sciences

Mjesto i datum
Primošten, Hrvatska, 1-5.09.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
genome annotation; hierarchical multi-label classification; phylogenetic profiling

Sažetak
GORBI is an online database offering the results of computational gene function prediction in prokaryotic genomes. The analysis was done via the method of correlating gene occurrence patterns in selected organisms, termed phylogenetic profiling [1]. A machine learning algorithm based on decision trees for hierarchical multi-label classification [2] was used, and the annotations are represented in using the Gene Ontology vocabulary. The web interface will be used to present the results of our previous analyses in a clear and easily browsable accessible manner, thereby covering two angles in wet lab research: focusing on 1) function (needing prediction for genes having that function in any organism), and 2) organism (needing prediction of any function in this particular organism). The layout of the interface is shown in the figure. An early version of GORBI is freely available from http://gorbi.irb.hr/ 1. Kensche, P.R., et al., Practical and theoretical advances in predicting the function of a protein by its phylogenetic distribution. Journal of the Royal Society Interface, 2008. 5(19): p. 151-170. 2. Vens, C., et al., Decision trees for hierarchical multi-label classification. Machine Learning, 2008. 73(2): p. 185-214.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Računarstvo

Napomena
Received the Best Poster Award of the 3rd CompSoLS Meeting.



POVEZANOST RADA


Projekti:
098-0982913-2862 - Molekularni mehanizmi rekombinacije i popravka DNA (Zahradka, Davor, MZOS ) ( POIROT)
098-0000000-3168 - Strojno učenje prediktivnih modela u računalnoj biologiji (Šmuc, Tomislav, MZOS ) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Nives Škunca (autor)

Avatar Url Fran Supek (autor)

Avatar Url Tomislav Šmuc (autor)

Avatar Url Jelena Repar (autor)

Citiraj ovu publikaciju

Supek, Fran; Šmuc, Tomislav; Repar, Jelena; Škunca, Nives
GORBI: Web application for the prediction of a protein's functional context // The 3rd Adriatic Meeting on Computational Solutions in the Life Sciences - Book of Abstracts / Babić, Darko ; Došlić, Nađa ; Smith, David ; Tomić, Sanja ; Vlahoviček, Kristian (ur.).
Zagreb: Centre for Computational Solutions in the Life Sciences, 2009. str. 76-76 (poster, međunarodna recenzija, sažetak, znanstveni)
Supek, F., Šmuc, T., Repar, J. & Škunca, N. (2009) GORBI: Web application for the prediction of a protein's functional context. U: Babić, D., Došlić, N., Smith, D., Tomić, S. & Vlahoviček, K. (ur.)The 3rd Adriatic Meeting on Computational Solutions in the Life Sciences - Book of Abstracts.
@article{article, year = {2009}, pages = {76-76}, keywords = {genome annotation, hierarchical multi-label classification, phylogenetic profiling}, isbn = {978-953-6690-80-0}, title = {GORBI: Web application for the prediction of a protein's functional context}, keyword = {genome annotation, hierarchical multi-label classification, phylogenetic profiling}, publisher = {Centre for Computational Solutions in the Life Sciences}, publisherplace = {Primo\v{s}ten, Hrvatska} }
@article{article, year = {2009}, pages = {76-76}, keywords = {genome annotation, hierarchical multi-label classification, phylogenetic profiling}, isbn = {978-953-6690-80-0}, title = {GORBI: Web application for the prediction of a protein's functional context}, keyword = {genome annotation, hierarchical multi-label classification, phylogenetic profiling}, publisher = {Centre for Computational Solutions in the Life Sciences}, publisherplace = {Primo\v{s}ten, Hrvatska} }




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