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Antimetastatic effect o propolis, caffeic acid phenethyl ester and caffeic acid on mammary carcinoma of CBA mouse (CROSBI ID 557385)

Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija

Bašić, Ivan ; Oršolić, Nada ; Tadić, Zoran ; Macedo Fereire, Alcici ; Brbot-Šaranović, Ana ; Bendelja, Krešo ; Krsnik, Boris ; Rabatić, Sabina Antimetastatic effect o propolis, caffeic acid phenethyl ester and caffeic acid on mammary carcinoma of CBA mouse // 17th International Cancer Congress Book of Papers / Moraes, Markos ; Brentani, Ricardo ; Bevilacqua, Ruy (ur.). Bolonja: Monduzzi Editore, 1998. str. 63-75

Podaci o odgovornosti

Bašić, Ivan ; Oršolić, Nada ; Tadić, Zoran ; Macedo Fereire, Alcici ; Brbot-Šaranović, Ana ; Bendelja, Krešo ; Krsnik, Boris ; Rabatić, Sabina

engleski

Antimetastatic effect o propolis, caffeic acid phenethyl ester and caffeic acid on mammary carcinoma of CBA mouse

We have studied the antimetastatic efficacy of water-soluble derivative of Brazilian or Croatian propolis (WSDP) and compared it with antimetastatic effect of caffeic acid phenethyl ester (CAPE) or with caffeic acid (CA). In vitro cytotoxicity of these compounds on tumor cells were also studied. Tumor was a transplantable mammary carcinoma (MCA). Metastases in the lung were generated by injecting .2 X 105 viable tumor cells iv: tested compounds were given po before or after tumor cell inoculation. In in vitro studies V79 cells, HeLa cells or MeA cells were used. treatment of mice significantly reduced the number of tumor nodules in the lung. In invitro studies WSDP did not affect the growth of cells. while CAPE and CA expressed strong cytotoxic effect. Antitumor effect of WSDP was in part due to apoptosis of MCA cells.

Antimetastatic effect; propolis; caffeic acid; caffeic acid phenethyl ester

Zbornik kongresa registriran je u bazi podataka Current Contents Proceedings.

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Podaci o prilogu

63-75.

1998.

objavljeno

Podaci o matičnoj publikaciji

17th International Cancer Congress Book of Papers

Moraes, Markos ; Brentani, Ricardo ; Bevilacqua, Ruy

Bolonja: Monduzzi Editore

978-88-3230-824-2

Podaci o skupu

17th International Cancer Congress

poster

23.08.1998-28.08.1998

Rio de Janeiro, Brazil

Povezanost rada

Temeljne medicinske znanosti, Veterinarska medicina, Biologija