engleski

Immunocytochemical and quantitative analysis of the gastrin cells in the rats with transplanted hypophyseal tumour

Endocrine cells in the antrum and duodenum of the rats with tranplanted mammotropic hypophyseal tumour (MtTB) were observed. Gastrin cells were demonstrated by using the unlabelde antibody and peroxidase- antiperoxidase (PAP) complex. Argyrophilic cells were analysed by the method after Grimelius. Stereological analysis was performed by means of the test system after Weibel. Calculation were made of the volume and numerical densities and average volume of the endocrine cells. The results indicate that the number of gastrin cells do not basically differ in the control and the experimental rats. In experimental group there occured a significant increase in the number of argyrophilic cells especially at the back of the antrum and in duodenum.

immunocytochemistry; gastrin cells; rat; hypophyseal tumour

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