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Pregled bibliografske jedinice broj: 437463

C282Y, H63D and S65C mutations of the hemochromatosis gene (HFE) in patients with alcoholic cirrhosis


Starčević Čizmarević, Nada; Stepec, Srećko; Ristić, Smiljana; Milić, Sandra; Brajenović-Milić, Bojana; Štimac, Davor; Kapović, Miljenko; Peterlin, Borut
C282Y, H63D and S65C mutations of the hemochromatosis gene (HFE) in patients with alcoholic cirrhosis // Abstract of the European Human genetics Conference, Eur J Hum Gen
Prague, 2005. (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
C282Y, H63D and S65C mutations of the hemochromatosis gene (HFE) in patients with alcoholic cirrhosis

Autori
Starčević Čizmarević, Nada ; Stepec, Srećko ; Ristić, Smiljana ; Milić, Sandra ; Brajenović-Milić, Bojana ; Štimac, Davor ; Kapović, Miljenko ; Peterlin, Borut

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract of the European Human genetics Conference, Eur J Hum Gen / - Prague, 2005

Skup
European Human genetics Conference

Mjesto i datum
Prag, Češka, 7-10.05.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Alcoholic cirrhosis; hemochromatosis; HFE gene mutations

Sažetak
We have investigated the contribution of genetic polymorphisms in the hemochromatosis gene to susceptibility for alcoholic liver disease in Croatian and Slovenian patients. The genotypes of alcoholics with and without cirrhosis, and healthy controls for the polymorphisms C282Y, H63D, and S65C suggested that C282Y and S65C mutations were not associated to the risk of developing alcoholic cirrhosis in our populations, while the frequency of H63D heterozygotes was significantly higher (P=0.0019) in patients with alcoholic cirrhosis (31.98%) than in healthy controls (19.14%).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE