Langerhans cells in the immunopathology of contact allergic dermatitis (CROSBI ID 157213)
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Podaci o odgovornosti
Lipozenčić, Jasna ; Lacković, Gordana ; Rode, Bojan ; Čajkovac, Vladimir
engleski
Langerhans cells in the immunopathology of contact allergic dermatitis
The functional morphology, topography and frequency of Langerhans cells (LCs), which are significant factors in the pathogenesis of contact allergic dermatitis (CAD), were studied by histoenzymatic methods (adenosine triphosphatase (ATP-ase), acid phosphatase (AF) and alphanaphtylacetate esterase (ANAE), immunohistochemical methods (indirect immunoperoxidase (IPO) with the monoclonal antibody OKT 6), and the peroxidase-antiperoxidase (PAP) method with the polyclonal S-100 antibody in skin biopsies of 24 patients with CAD, as well in skin biopsies in experimental models in guinea pigs. The results confirmed the significant role of "LCs“ in the pathogenesis of contact allergic dermatitis.
langerhans cells ; contact allergic dermatitis ; contact sensitivity ; enzyme histochemistry ; immunohistochemistry
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Podaci o izdanju
Povezanost rada
Biologija, Kliničke medicinske znanosti