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Pregled bibliografske jedinice broj: 437229

An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells


Kováčiková, Z.; Tátrai, E.; Piecková, E.; Tulinská, J.; Pivovarová, Z.; Mataušic-Pišl, Mirjana; Kuricová, M.; Wsolová, L.
An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells // ATLA. Alternatives to laboratory animals, 35 (2007), 1; 47-52 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 437229 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells

Autori
Kováčiková, Z. ; Tátrai, E. ; Piecková, E. ; Tulinská, J. ; Pivovarová, Z. ; Mataušic-Pišl, Mirjana ; Kuricová, M. ; Wsolová, L.

Izvornik
ATLA. Alternatives to laboratory animals (0261-1929) 35 (2007), 1; 47-52

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Alveolar macrophages; In vitro; Stachybotrys chartarum metabolites; Type II pneumocytes

Sažetak
During a study of indoor fungal colonisation, several isolates of Stachybotrys chartarum were recovered, and the effects of metabolites from four isolates on lung epithelial Type II cells and alveolar macrophages were studied in vitro. All the isolates showed toxic effects on both cell types, and they differed only in the extent of the changes induced. In Type II cells, the number of alkaline phosphatase positive cells was reduced, the pattern of Maclura pomifera agglutinin (MPA) binding was changed, and acid phosphatase activity in alveolar macrophages was diminished. In both cell types, the production of monocyte chemotactic protein-1 (MCP-1) and tumour necrosis factor-alpha (TNF-alpha) was changed, and parameters related to antioxidant status (superoxide dismutase, glutathione peroxidase, glutathione) were decreased.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
022-0222411-2406 - BIOLOŠKI POKAZATELJI DJELOVANJA ELEKTROMAGNETSKOG NEIONIZIRAJUĆEG ZRAČENJA (Trošić, Ivančica, MZOS ) ( POIROT)

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb

Profili:

Avatar Url Mirjana Mataušić-Pišl (autor)


Citiraj ovu publikaciju

Kováčiková, Z.; Tátrai, E.; Piecková, E.; Tulinská, J.; Pivovarová, Z.; Mataušic-Pišl, Mirjana; Kuricová, M.; Wsolová, L.
An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells // ATLA. Alternatives to laboratory animals, 35 (2007), 1; 47-52 (međunarodna recenzija, članak, znanstveni)
Kováčiková, Z., Tátrai, E., Piecková, E., Tulinská, J., Pivovarová, Z., Mataušic-Pišl, M., Kuricová, M. & Wsolová, L. (2007) An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells. ATLA. Alternatives to laboratory animals, 35 (1), 47-52.
@article{article, year = {2007}, pages = {47-52}, keywords = {Alveolar macrophages, In vitro, Stachybotrys chartarum metabolites, Type II pneumocytes}, journal = {ATLA. Alternatives to laboratory animals}, volume = {35}, number = {1}, issn = {0261-1929}, title = {An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells}, keyword = {Alveolar macrophages, In vitro, Stachybotrys chartarum metabolites, Type II pneumocytes} }
@article{article, year = {2007}, pages = {47-52}, keywords = {Alveolar macrophages, In vitro, Stachybotrys chartarum metabolites, Type II pneumocytes}, journal = {ATLA. Alternatives to laboratory animals}, volume = {35}, number = {1}, issn = {0261-1929}, title = {An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells}, keyword = {Alveolar macrophages, In vitro, Stachybotrys chartarum metabolites, Type II pneumocytes} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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