engleski

Smoking and schizophrenia

A large number of worldwide studies describing current smoking in schizophrenia consistently suggest that schizophrenic patients from all countries share a common biological factor, that makes them more prone to smoke (De Leon and Diaz, 2005). There is also evidence that cigarette smoking can reduce deficits relative to dopamine hypofunction in prefrontal cortex. All these data suggest that clinicians should consider smoking as an important factor in the disposition of these drugs. Namely, schizophrenic patients who smoke may require higher dosages of antipsychotics than nonsmokers. Conversely, upon smoking cessation, smokers may require a reduction in the dosage of antipsychotics.

cigarette smoking; schizophrenia; nicotine addiction

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