engleski

Psoriasis in pregnancy : a review of most important data from literature

Psoriasis is a common inflammatory skin disease characterized by infiltration of inflamatory cells into the epidermis and altered keratinocyte differentiation. Psoriasis affects about 25 million people in North America and Europe, and is probably the most prevalent immune-mediated skin disease in adults. Incidence is similar for the two sexes, although women generally develop the disease earlier than men. Because the majority of psoriasis patients present before the age of 40, many of the female patients may become pregnant. Information regarding the heritability of psoriasis can be used in counseling patients who inquire about the potential risk to their children. If one parent is affected by psoriasis, the risk to offspring is 14%-15%. If both parents have psoriasis, the risk to offspring is 41%-75%. If neither parent has the psoriasis but a child is affected, the risk to subsequent is 6%-20%.

psoriasis; pregnancy; prepregnancy time; safety therapeutic options

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