First report of methicillin-resistant Staphylococcus pseudintermedius in Croatia (CROSBI ID 555090)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Matanović, Krešimir ; Šeol, Branka ; Mekić, Selma
engleski
First report of methicillin-resistant Staphylococcus pseudintermedius in Croatia
Staphylococcus pseudintermedius is an opportunistic pathogen most frequently isolated from canine and feline skin and ear infections. Methicillin resistance in staphylococci is mediated by mecA gene, which encodes for production of an altered penicillin binding protein that has a low affinity for all beta-lactam antibiotics. Methicillin-resistant Staphylococcus aureus (MRSA) is a tremendous problem both in human and veterinary medicine ; however methicillin-resistant S. pseudintermedius (MRSP) is emerging as a significant threat in household pets and is reported more frequently during last years. From November 2008 to June 2009 seven multiresistant S. pseudintermedius strains were isolated from external ear canal (2), pharynx, nasal cavity, skin (2) and conjunctival sac of diseased dogs and one strain from a pharynx of diseased cat. They were identified on the basis of biochemical properties. All isolates were DNase and coagulase positive, clumping factor negative or weakly positive, hemolytic on blood agar and produced beta-galactosidase, while none of them produced acetoin. Antibiotic susceptibility testing was performed by disc diffusion on Mueller-Hinton agar according to CLSI guidelines. All strains were resistant to methicillin, oxacillin, penicillin, amoxicillin-clavulanic acid, cefalexin, cefovecin, gentamicin, lincomycin, clindamycin, erythromycin, enrofloxacin, ciprofloxacin, marbofloxacin and trimethoprim-sulfamethoxazole and, with the exception of one, to chloramphenicol. All strains were susceptible to mupirocin, bacitracin, rifampicin, fucidic acid and amikacin, and all except one to tetracycline. Multidrug-resistant MRSP represent a challenge for antimicrobial therapy in veterinary medicine due to the limited treatment options and absence of effective antimicrobials labeled for use in animals.
methicillin resistant; Staphylococcus pseudintermedius; Croatia
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Podaci o prilogu
65-65.
2009.
objavljeno
Podaci o matičnoj publikaciji
Central European Symposium on Antimicrobial Resistance - CESAR 2009
Maravić Vlahoviček, Gordana
Zagreb: Hrvatsko mikrobiološko društvo
978-953-96567-9-3
Podaci o skupu
Central European Symposium on Antimicrobial Resistance-CESAR 2009
poster
23.09.2009-26.09.2009
Zadar, Hrvatska