Esomeprasole versus Pantoprazole for healing erosive oesophagitis (CROSBI ID 155628)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Včev, Aleksandar ; Begić, Ivana ; Ostojić, Rajko ; Jurčić, Dragan ; Božić, Dubravko ; Soldo, Ivan ; Gmajnić, Rudika ; Kondža, Goran ; Khaznadar, E. ; Mićunović, Nikola
engleski
Esomeprasole versus Pantoprazole for healing erosive oesophagitis
The aim of this study was to compare the efficacy of esomeprazole and pantoprazole with regard to healing and relief from gastroesophageal reflux disease-related symptoms. In this multicentre, randomized, single-blind study 180 patients ( ITT population ) diagnosed with endoscopically proven GERD grade A, B, C received esomeprazole ( 40 mg once daily (o.d), n=90 ) or pantoprazole ( 40 mg o.d., n= 90 ). Healing and relief from GERD-related symptoms were assessed at first and final visit ( after 4 or 8 weeks of treatment ). Esomeprazole 40 mg provided significantly greater healing than pantoprazole 40 mg after 4 weeks of treatment in patients with EE ( 77.8 % vs. 91.1 % ). The proportion of heartburn-free days was similar in patients treated with esomeprazole and to those treated with pantoprazole.
GERD; esomeprazole; pantoprazole
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Podaci o izdanju
30 (3)
2006.
519-522
objavljeno
1330-4917