IS1245-RFLP based genetic relatedness of the Mycobacterium avium subsp. hominissuis strains isolated from humans, animals and environment in Croatia (CROSBI ID 554164)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Špičić, Silvio ; Cvetnić, Željko ; Pate, Mateja ; Katalinić-Janković, Vera ; Duvnjak, Sanja ; Ocepek, Matjaž ; Zdelar-Tuk, Maja ; Krt, Brane
engleski
IS1245-RFLP based genetic relatedness of the Mycobacterium avium subsp. hominissuis strains isolated from humans, animals and environment in Croatia
Significance of infections with Mycobacterium avium, in particular subspecies M. a. hominissuis, in animals and humans is constantly increasing. Susceptibility of humans, cattle and swine to various mycobacteria and the prevalence of these bacteria in the environment, although very important from the aspect of epizootiology and epidemiology, have not been sufficiently investigated in Croatia. This study is based on massive tuberculin skin tests of cattle and swine from large farms, bacteriology and molecular identification of M. a.hominissuis isolated from domestic and wild animals, humans and environment. Genotyping of the 23 isolates was conducted by IS1245 RFLP method. The selected cut-off value for cluster designation was similarity level of 75%. A total of 5 clusters containing 86.9 % of all genotyped strains were identified. High similarity level of the profiles within a cluster was found for the isolates from man, swine from intensive breeding, deer, wild boar and sawdust from various counties. As no epizootiological links between animals and humans were identified, humans and animals could be considered as dead-end hosts. According to our results, the source of infection for humans and animals is most probably the environment.
Mycobacterium avium subsp. hominissuis; RFLP
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Podaci o prilogu
2009.
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objavljeno
Podaci o matičnoj publikaciji
ESM 30th Annual Congress, Porto, Portugal
Suzana David
Porto:
Podaci o skupu
European Society of Mycobacteriology 30th Annual Congress
poster
05.07.2009-08.07.2009
Porto, Portugal