Y-chromosome STR haplotypes in a population sample from Eastern Croatia (CROSBI ID 554155)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Gršković, Branka ; Merkaš, Siniša ; Polašek, Ozren ; Mršić, Gordan
engleski
Y-chromosome STR haplotypes in a population sample from Eastern Croatia
A population genetic analysis of the 17 Y-chromosome short tandem repeats (STR) loci in the Eastern Croatia region. A total of two hundred and twenty unrelated healthy men from the Eastern Croatia were included in the study. Genomic DNA was extracted using Chelex procedure from FTA cards. Y-chromosomal STRs were determined using the AmpFlSTR Yfiler PCR amplification kit that coamplifies 17 Y-STRs (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATAH4). The haplotype frequencies were determined by direct counting and analyzed using Arlequin 3.1. A total of 207 haplotypes were recorded, 197 of which were unique (89.55%). Haplotype diversity was 0.9993, with the commonest recorded haplotype being shared by only four recruits. Locus diversity varied from 0.256 for DYS392 to 0.780 for DYS458. Average locus diversity was 0.600. This is the first attempt to describe the genetic structure of a sample of the inhabitants of Eastern parts of Croatia, which may serve as the standard for various genetic epidemiology and forensic studies. Further studies are needed to characterize the genetic structure of the entire Croatian population in order to create an authoritative overview of the modern Croatian population. The results reported herein are of great importance for paternity testing, forensic casework on sexual assault evidence as well as individual identification.
Y chromosome; short tandem repeats; population genetics; haplotypes; Eastern Croatia
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Podaci o prilogu
83-x.
2009.
objavljeno
Podaci o matičnoj publikaciji
Final program and abstracts The 6th ISABS Conference on Human Genome Project based applications in Forensic Science, Anthropology and Individualized Medicine/Schanfield, Moses ; Primorac, Dragan ; Vuk-Pavlović, Stanimir (ur.). - Split : ISABS , 2009. 171-171.
Podaci o skupu
The 6th ISABS Conference on Human Genome Project based aapplications in Forensic Science, Anthropology and Individualized Medicine
poster
01.06.2009-05.06.2009
Split, Hrvatska