engleski

In vitro susceptibility of field isolates of Mycoplasma conjunctivae to some antimicrobial agents

The most of 9 tested antimicrobial agents showed considerable in vitro effectiveness against tested M. conjunctivae isolates. The most effective were enrofloxacin, tiamulin, chlortetracycline and oxytetracycline, followed by tylosin and gentamicin. The highest resistance was recorded with chloramphenicol, neomycin, and streptomycin Until now only a limited number of reports on sensitivity testing of M. conjunctivae isolates are available. Remarkable in vitro sensitivity of our M. conjunctivae isolates to tetracyclines was verified by good results obtained by topic and systemic administration of these drugs during the first outbreak of ovine infectious keratoconjunctivitis in Croatia. It can be concluded from our study that enrofloxacin, tiamulin, tetracyclines and tylosin are promising for the local and/or systemic treatment of IKC in small ruminants. Taking into account the broader antibacterial activity and possibilities of incorporation in ophthalmic preparations, tetracyclines may be preferred.

Mycoplasma conjunctivae; antimicrobial agents

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