engleski

Synthesis and Antitiumor Activity of N-Sulfonyl Derivatives of Nucleobases and Sulfonamido Nucleoside Derivatives

The introduction of sulfonamido group on the C-2 position of pyrimidine nucleosides was achieved by ring opening of 2, 2'- and 2, 3'-anhydronucleosides. N-sulfonyl derivatives of nucleobases and sulfonamido derivatives of nucleosides were assayed for in vitro antitumor activity.

Anhydronucleosides; C-2 sulfonamido pyrimidine nucleosides; in vitro antitumor activity ;

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