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Pregled bibliografske jedinice broj: 420793

In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test


Mekić, Selma; Šeol, Branka; Matanović, Krešimir
In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test // Microbes and Man-independence and future challenges
Goeteborg, 2009. (poster, sažetak, znanstveni)


Naslov
In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test

Autori
Mekić, Selma ; Šeol, Branka ; Matanović, Krešimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Microbes and Man-independence and future challenges / - Goeteborg, 2009

Skup
FEMS 2009 3rd Congress of Euroean Microbiologists

Mjesto i datum
Goeteborg, Švedska, 28.06.-2.07. 2009.

Vrsta sudjelovanja
Poster

Vrsta recenzije
Neobjavljeni rad

Ključne riječi
Pseudomonas aeruginosa; E-test

Sažetak
Background: Infections with antimicrobial-resistant bacteria are a great challenge in both human and veterinary medicine. Pseudomonas aeruginosa, an opportunistic, ubiquitous bacterial pathogen is becoming increasingly important due to its antibiotic resistance and ability to cause serious infections in animals and people. Objectives: Comparison of in vitro activities of enrofloxacin, ciprofloxacin, ticarcillin, ceftazidime, gentamicin and cefepime against 96 strains of P. aeruginosa isolated from dogs with otitis externa during the years from 1999 to 2008. Methods: Antimicrobial susceptibility was evaluated by E test1 in accordance with the guidelines of the National Committee for Clinical Laboratory Standards. Results: The most active compound in vitro was ceftazidime with 100% efficiency. The majority of tested strains were susceptible to ticarcillin (89.58%), followed by ciprofloxacin (87.50%), cefepime (58.33%) and gentamicin (56.25%). The highest resistance was observed towards enrofloxacin (53.13%), cefepime (33.33%), gentamicin (18.75%), ticarcillin (10.42%) and ciprofloxacin (9.38%). Only one strain (1.04%) showed sensitivity to enrofloxacin. Conclusions: This study showed that among all tested antimicrobial agents, ceftazidime was the most effective against P. aeruginosa strains. At the same time resistance to enrofloxacin was unexpectedly high.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina



POVEZANOST RADA


Projekt / tema
053-0481153-1129 - Mikoplazmoze i neke uvjetovane infekcijske bolesti životinja (Branka Šeol, )

Ustanove
Veterinarski fakultet, Zagreb