Estimation of axial dispersion in horizontal rotating tubular bioreactor by means of a structured model (CROSBI ID 86890)
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Podaci o odgovornosti
Šantek, Božidar ; Horvat, Predrag ; Novak, Srđan ; Sunko, Denis K. ; Moser, Anton ; Marić, Vladimir
engleski
Estimation of axial dispersion in horizontal rotating tubular bioreactor by means of a structured model
A horizontal rotating tubular bioreactor (HRTB) is designed as the combination of a thin-layer bioreactor and a biodisc reactor. The investigation of mixing in HRTB was done by the temperature step method in a wide range of process conditions [residence time (t_Z = 3600 - 36000 s) and bioreactor rotation speed (n = 0.083 - 0.917 s^-1)]. In all experiments heat losses were detected. A mathematical model based on tank in series concept was developed to described the mixing in HRTB - a spiral flow model (SFM) which has incorporated heat losses. However, the simulations of SFM could be used for calculation of temperature response curves for the case when there is no heat losses. These corrected curves were used then to estimate Bodenstein number as a parameter of standard dispersion model (SDM). Obtained Bodenstein numbers were in the range 10 - 17. The simulations had shown that SFM was more capable to describe the mixing in HRTB giving better fitting with experimental measurements then SDM, indicating that mixing pattern in HRTB is to complex to be described with this relatively simple, one-parameter model.
mixing; horizontal rotating tubular bioreactor (HRTB); axial dispersion model; spiral flow model
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