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Aseptic meningitis, sensorineural hearing loss induced by simultaneous use of ibuprofen and ciprofloxacin (CROSBI ID 553248)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Sepčić, Juraj ; Materljan, Eris ; Šepić Grahovac, Dubravka ; Jurjević, Ante Aseptic meningitis, sensorineural hearing loss induced by simultaneous use of ibuprofen and ciprofloxacin // Acta Neuropsychiatrica. Proceedings. 49 th International Neuropsychiatric Pula Congress (INPC) / Vida Demarin, Vanja Bašić Kes, Zlatko Trkanjec (ur.). Wiley-Blackwell, 2009. str. 78-x

Podaci o odgovornosti

Sepčić, Juraj ; Materljan, Eris ; Šepić Grahovac, Dubravka ; Jurjević, Ante

engleski

Aseptic meningitis, sensorineural hearing loss induced by simultaneous use of ibuprofen and ciprofloxacin

Aseptic meningitis (AM), with or without other drug-induced neurological disorders, has been the subject of several reviews. We report clinically rare and serious adverse reactions that occurred after the co-administration of Ibuprofen and Ciprofloxacin: completely reversible aseptic meningitis and irreversible bilateral hearing loss, tinnitus , and vestibulopathy. Recurrent urinary inflammation treated with antibiotics, classic migraine, and allergy to trimethoprim-sulfamethoxazole and chromium were favorable predisposing factors for the adverse event in this patient. A close chronological relation between administration of drugs (especially Ibuprofen) and adverse reactions was noted. No evidence of infection and/or autoimmune disease was found. The mechanism of these serious events may be explained as a hypersensitive reaction affecting the meanings and, partially, cochlea.

Aseptic meningitis; sensorineural hearing loss; ibuprofen; ciprofloxacin

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Podaci o prilogu

78-x.

2009.

objavljeno

Podaci o matičnoj publikaciji

Acta Neuropsychiatrica. Proceedings. 49 th International Neuropsychiatric Pula Congress (INPC)

Vida Demarin, Vanja Bašić Kes, Zlatko Trkanjec

Wiley-Blackwell

Podaci o skupu

49 th International Neuropsychiatric Pula Congress (INPC)

poster

17.06.2009-20.06.2009

Pula, Hrvatska

Povezanost rada

Kliničke medicinske znanosti, Farmacija