Aseptic meningitis, sensorineural hearing loss induced by simultaneous use of ibuprofen and ciprofloxacin (CROSBI ID 553248)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Sepčić, Juraj ; Materljan, Eris ; Šepić Grahovac, Dubravka ; Jurjević, Ante
engleski
Aseptic meningitis, sensorineural hearing loss induced by simultaneous use of ibuprofen and ciprofloxacin
Aseptic meningitis (AM), with or without other drug-induced neurological disorders, has been the subject of several reviews. We report clinically rare and serious adverse reactions that occurred after the co-administration of Ibuprofen and Ciprofloxacin: completely reversible aseptic meningitis and irreversible bilateral hearing loss, tinnitus , and vestibulopathy. Recurrent urinary inflammation treated with antibiotics, classic migraine, and allergy to trimethoprim-sulfamethoxazole and chromium were favorable predisposing factors for the adverse event in this patient. A close chronological relation between administration of drugs (especially Ibuprofen) and adverse reactions was noted. No evidence of infection and/or autoimmune disease was found. The mechanism of these serious events may be explained as a hypersensitive reaction affecting the meanings and, partially, cochlea.
Aseptic meningitis; sensorineural hearing loss; ibuprofen; ciprofloxacin
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Podaci o prilogu
78-x.
2009.
objavljeno
Podaci o matičnoj publikaciji
Acta Neuropsychiatrica. Proceedings. 49 th International Neuropsychiatric Pula Congress (INPC)
Vida Demarin, Vanja Bašić Kes, Zlatko Trkanjec
Wiley-Blackwell
Podaci o skupu
49 th International Neuropsychiatric Pula Congress (INPC)
poster
17.06.2009-20.06.2009
Pula, Hrvatska