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Microlithiasis as a common cause of recurrent acute pancreatitis


Kujundžić, Milan; Bilić, Branko; Bogdanović, Zoran; Bokun, Tomislav; Banić, Marko; Babić, Žarko; Kardum, Duško; Grgurević, Ivica; Crnčević-Urek, Marija; Tadić, Mario et al.
Microlithiasis as a common cause of recurrent acute pancreatitis // Abstracts of the 16th United European Gastroenterology Week (UEGW 2008) ; u: Gut 57 (2008) (S2)
Beč, Austrija: Gut, 2008. str. A399-A399 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Microlithiasis as a common cause of recurrent acute pancreatitis

Autori
Kujundžić, Milan ; Bilić, Branko ; Bogdanović, Zoran ; Bokun, Tomislav ; Banić, Marko ; Babić, Žarko ; Kardum, Duško ; Grgurević, Ivica ; Crnčević-Urek, Marija ; Tadić, Mario ; Petričušić, Lidija ; Puljiz, Željko.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 16th United European Gastroenterology Week (UEGW 2008) ; u: Gut 57 (2008) (S2) / - : Gut, 2008, A399-A399

Skup
United European Gastroenterology Week (16 ; 2008)

Mjesto i datum
Beč, Austrija, 18.-22.10.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Microlithiasis; ERCP

Sažetak
Despite new diagnostic advantages of EUS and MRCP the cause of recurrent acute pancreatitis in many cases remains unknown. The role of microlithasis has been widely debated. The aim of our study was to determine if microlithasis is one of the causes in recurrent and idiopathic acute pancreatitis. During a period of 5 years, we analyzed a total of 47 patients that suffered from at least one or more attacks of idiopathic pancreatitis. All patients underwent an trans-abdominal ultrasound of the abdomen (US), endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP) before the endoscopic retrograde cholangiopancreatography (ERCP) was performed. Prior to the injection of contrast into common bile duct, a bile sample was taken for microscopic analysis. Positive finding were samples with two or more microlithes per 100X field. Totally 47 patient were diagnosed with recurrent and idiopathic acute pancreatitis. After an entire diagnostic work up was done, an ERCP was performed on all 47 patients. A total of 31 patients (66%) was found to have a microlithiasis. Sphincterectomy was performed on all patients with microlithiasis. Attacks of recurrent pancreatitis were followed during the period of 2 years. Moreover, 7 out of 31 positive on microlithiasis, were found to have a high degree of suspicion on microlithiasis of the gall bladder. All of them were treated with laparoscopic cholecystectomy. Twenty nine out of 31 with microlithiasis and after sphincterectomy had no recurrent episode of acute pancreatitis, while two did. Our results show that microlithiasis is, in many cases (66%), the cause of recurrent acute pancreatitis. Sphincterotomy seems to be the optimal therapeutic option and preventive measure.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-0000000-3114 - HELICOBAKTER PYLORI INFEKCIJA - EVOLUCIJA BOLESTI I NOVI TERAPIJSKI POSTUPCI (Miroslava Katičić, )
198-0000000-1124 - Bolesti pankreato-bilijarnog sustava: etiologija, dijagnostika i terapija (Milan Kujundžić, )
198-0000000-3103 - C-reaktivni protein i gastroduodenalno oštećenje u koronarnih bolesnika (Marko Banić, )

Ustanove
Medicinski fakultet, Zagreb,
Klinička bolnica "Dubrava"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE