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Pregled bibliografske jedinice broj: 417343

Renal involvement in a small-vessel vasculitis


Tišljar Miroslav; Prkačin, Ingrid; Ljubanović, Danica; Galešić, Krešimir
Renal involvement in a small-vessel vasculitis // APMIS
Oxford: Wiley-Blackwell, 2009. str. 150-150 (poster, međunarodna recenzija, sažetak, stručni)


Naslov
Renal involvement in a small-vessel vasculitis

Autori
Tišljar Miroslav ; Prkačin, Ingrid ; Ljubanović, Danica ; Galešić, Krešimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
APMIS / - Oxford : Wiley-Blackwell, 2009, 150-150

Skup
14th International ANCA Workshop

Mjesto i datum
Lund, Švedska, Kopenhagen, Danska, 06-09.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Small-vessel vasculitis; pauci-imune glomerulonephritis

Sažetak
Background: Renal involvement is common in a small vessel vasculitis and could be dominant picture of disease. ANCA associated small vessel vasculitis (AASV) is the most frequent kind of vasculitides in adults. Objective: To present clinical-laboratory features and histopathological characteristics of our 25 patients with renal involvement due to small vessel vasculitides. Patients and Methods: In this retrospecitve study (from 2005. to 2008.) we present 25 patients with clinical-laboratory features of renal disorder, who underwent renal biopsy followed by histo-logical tissue specimens examination (light, imunoflourescence, electronic microscopy). Indications for renal biopsy were nephritic syndrome, nephrotic-nephritic syndrome, nephrotic syndrome in 14, 10, 1 patients, respectively. In all patients serum creatinine level, 24h proteinuria, urine sediment, serum ANCA level (ELISA) and VDI (Vasculitis Damage Index) were determinated. Results: This retrospective study included 25 patients (15 male and 10 female) average age of 54 years (from 19 to 79) with histological evidence of pauci-immune focal or diffuse necrotising cresentic glomerulonephritis. Twenty patients had nephritic urine sediment and four had oliguria. Average 24h proteinuria was 3, 54 g and an average serum creatinine value of 352 &micro ; ; ; ; ; mol/L. Average CRP level was 22 mg/L. pANCA was positive in 8 patients, cANCA in 2 and cANCA+pANCA in 1. Microscopic polyangiitis (MP) was confirmed in 12 patients, renal limited MP in 10 and Wegener granulomatosis (WG) in 3 patients. VDI score ranged from 3 to 8. Conclusion: In this study we present 12 patients with microscopic polyangiitis, 10 with renal limited MP and 3 with WG. pANCA was positive in 8 patients (32%), cANCA in 2 (8%) and cANCA+pANCA in 1 (4%).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
198-0000000-0179 - Prognostički čimbenici progresije bubrežne insuficijencije (Krešimir Galešić, )
198-0000000-3355 - Značaj morfoloških čimbenika u dijagnostici, terapiji i prognozi FSGS (Danica Galešić-Ljubanović, )

Ustanove
Klinička bolnica "Dubrava"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE