Viral inhibitors of NKG2D ligands : friends or foes of immune surveillance? (CROSBI ID 152994)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Jonjić, Stipan ; Polić, Bojan ; Krmpotić, Astrid
engleski
Viral inhibitors of NKG2D ligands : friends or foes of immune surveillance?
NKG2D is a potent activating receptor on NK cells and a co-stimulatory receptor on CD8+ T cells. Through its ability to recognize a panel of ligands inducible by stress or infection, it plays an important role in the control of viral infections. The viruses have evolved robust mechanisms to counteract NKG2D-dependent immune response. The functions of these viral inhibitors are well characterized during the early days post-infection but less so during the chronic viral infection.
NKG2D ligands; immunoevasion; tumor; virus
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