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Pregled bibliografske jedinice broj: 409902

Bone Morphogenetic Proteins: From Local to Systemic Therapeutics


Bone Morphogenetic Proteins: From Local to Systemic Therapeutics, Basel, Boston, Berlin: Birkhauser Verlag AG, 2008 (zbornik)


Naslov
Bone Morphogenetic Proteins: From Local to Systemic Therapeutics

Urednik/ci
Vukicevic, Slobodan ; Sampath TK

Vrsta, podvrsta i kategorija knjige
Uredničke knjige, zbornik, znanstvena

Izdavač
Birkhauser Verlag AG

Grad
Basel, Boston, Berlin

Godina
2008

Stranica
343

ISBN
978-3-7643-8551-4

Ključne riječi
bone morphogenetic proteins

Sažetak
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs. In this volume, we summarized the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic use of BMPs for tissues beyond bone. This volume is of interest to researchers from immunology, cell biology, biochemistry, and clinicians from orthopedics and dentistry, as well as to research managers from biotech and pharmaceutical companies.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekt / tema
108-1080327-0320 - Uloga TSH u modelu osteoporoze i u bolesnica sa smanjenom koštanom masom (Slobodan Vukičević, )

Ustanove
Medicinski fakultet, Zagreb

Profili:

Avatar Url Slobodan Vukičević (urednik)

Citiraj ovu publikaciju

Bone Morphogenetic Proteins: From Local to Systemic Therapeutics, Basel, Boston, Berlin: Birkhauser Verlag AG, 2008 (zbornik)
Vukicevic, S. & Sampath TK (ur.) (2008) Bone Morphogenetic Proteins: From Local to Systemic Therapeutics. Basel, Boston, Berlin, Birkhauser Verlag AG.
@book{book, editor = {Vukicevic, S. and Sampath TK}, year = {2008}, pages = {343}, keywords = {bone morphogenetic proteins}, isbn = {978-3-7643-8551-4}, title = {Bone Morphogenetic Proteins: From Local to Systemic Therapeutics}, keyword = {bone morphogenetic proteins}, publisher = {Birkhauser Verlag AG}, publisherplace = {Basel, Boston, Berlin} }