engleski

Population data on the X chromosome short tandem repeat loci DXs9895, GAtA172D05, DXs6810, DXs6803 and HPRt in croatia

Due to its high polymorphism, the analysis of Short Tandem Repeat (STR) markers using the PCR method has become a widely applied technique in forensic individual identification, rapid detection of chromosome aneuploidies in prenatal and postnatal diagnosis and paternity testing. Until now a large number of autosomal and Y-chromosomal markers has been forensically evaluated and used for various purposes, but the application of X-chromosomal markers has played only a minor role in forensic practice so far. The X-STR loci (DXS9895, GATA172D05, DXS6810, DXS6803 and HPRT) were investigated in male (N=90) and female (N=93) population samples from Croatia. Samples were collected from randomly selected unrelated healthy individuals. No deviation from the Hardy-Weinberg equilibrium could be detected and allele frequencies showed similar distribution in male and female samples. With the exception of DXS6810 locus for which only 6 alleles were observed and PIC value lover than 0.75 was calculated, all other loci have demonstrated sufficient polymorphism and PIC value to be considered valuable in future forensic analyses.

X-STR; Croatia

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