engleski

Human Papillomavirus Genotype Specificity of Hybrid Capture 2 Low-risk Probe Cocktail

Genotyping study on 285 Hybrid Capture 2 (hc2) low-risk probe cocktail positive specimens showed cross-reactivity with several untargeted HPV genotypes. Cross-reactivity was often clinically beneficial due to detection of untargeted low-risk genotypes. 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of grey-zone is recommended.

HPV; hybrid capture 2; low risk genotypes

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