Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 40706

A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity


Basak, S.C.; Gute, B.D.; Lučić, Bono; Nikolić, Sonja; Trinajstić, Nenad
A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity // Computers and chemistry, 24 (2000), 2; 181-191 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 40706 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity

Autori
Basak, S.C. ; Gute, B.D. ; Lučić, Bono ; Nikolić, Sonja ; Trinajstić, Nenad

Izvornik
Computers and chemistry (0097-8485) 24 (2000), 2; 181-191

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
-

Sažetak
A novel QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity is reported and a new efficient method for selecting descriptors is used. Complement-inhibitory activity QSAR models of benzamidines contain from one to five descriptors. The best, according to fitted and cross-validated statistical parameters, is shown to be the five-descriptor model. Models with a higher number of indices did not improve over the five-descriptor model. The benzene derivatives structure-toxicity models involve up to seven linear descriptors. Multiregression models, containing up to ten nonlinear descriptors, are also reported for the sake of comparison with previously obtained additivity models.Comparison with benzamidine complement-inhibitory activity models and with benzene derivatives toxicity models from the literature favors our novel approach.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
00980606

Ustanove
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Bono Lučić (autor)

Avatar Url Sonja Nikolić (autor)

Avatar Url Nenad Trinajstić (autor)

Citiraj ovu publikaciju

Basak, S.C.; Gute, B.D.; Lučić, Bono; Nikolić, Sonja; Trinajstić, Nenad
A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity // Computers and chemistry, 24 (2000), 2; 181-191 (međunarodna recenzija, članak, znanstveni)
Basak, S., Gute, B., Lučić, B., Nikolić, S. & Trinajstić, N. (2000) A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity. Computers and chemistry, 24 (2), 181-191.
@article{article, year = {2000}, pages = {181-191}, keywords = {-}, journal = {Computers and chemistry}, volume = {24}, number = {2}, issn = {0097-8485}, title = {A comparative QSAR study of benzamidines complement-inhibitory activity and benzene derivatives acute toxicity}, keyword = {-} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Chemical Abstracts