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Pregled bibliografske jedinice broj: 406430

Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men


Tedeschi-Reiner, Eugenia; Iveković, Renata; Novak Lauš, Katia; Reiner, Željko
Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men // Medical science monitor, 15 (2009), 5; CR211-CR216 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 406430 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men

Autori
Tedeschi-Reiner, Eugenia ; Iveković, Renata ; Novak Lauš, Katia ; Reiner, Željko

Izvornik
Medical science monitor (1234-1010) 15 (2009), 5; CR211-CR216

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
retina; atherosclerosis; progesterone; estradiol; dehydroepiandrosterone sulfate

Sažetak
Increasing evidence suggests that both male and female sex hormones may be associated with the development of atherosclerosis, but almost all such data are based on studies of patients with coronary artery disease. To our knowledge, there are no data on the effects of endogenous sex hormones on atherosclerosis of the retinal arteries in men, and the purpose of this study was to explore that association. In 101 consecutive adult male patients treated in a university hospital outpatient clinic, atherosclerotic changes of the retinal vessels were identified prospectively by direct ophthalmoscopy and were graded on a scale of 1 to 4 according to Scheie. Commercial radioimmunoassay kits were used to measure serum levels of testosterone, estradiol, progesterone, androstenedione, and dehydroepiandrosterone sulfate. The chi-square test was used to compare the results with those from 47 matched male subjects with healthy retinal vessels. Retinal vessel atherosclerosis was inversely correlated with the serum progesterone concentration (P<0.001). The lower the progesterone concentration, the more advanced the stage of retinal vessel disease. A similar but less statistically significant correlation was noticed for dehydroepiandrosterone sulfate (P<0.05). A weak (P<0.05) similar association between the degree of retinal artery atherosclerosis and estradiol levels was also found. Low endogenous progesterone levels and, to a degree, low dehydroepiandrosterone sulfate and estradiol levels might be associated with atherosclerosis of the retinal arteries in men.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080134-0121 - Percepcija i prevencija čimbenika rizika za aterosklerozu u Hrvatskoj (Reiner, Željko, MZOS ) ( POIROT)
134-1340236-0181 - Distiroidna orbitopatija i glaukom (Iveković, Renata, MZOS ) ( POIROT)
134-1340236-0185 - Rano otkrivanje primarnog glaukoma otvorenog kuta (Novak-Lauš, Katia, MZOS ) ( POIROT)

Ustanove:
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Tedeschi-Reiner, Eugenia; Iveković, Renata; Novak Lauš, Katia; Reiner, Željko
Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men // Medical science monitor, 15 (2009), 5; CR211-CR216 (međunarodna recenzija, članak, znanstveni)
Tedeschi-Reiner, E., Iveković, R., Novak Lauš, K. & Reiner, Ž. (2009) Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men. Medical science monitor, 15 (5), CR211-CR216.
@article{article, year = {2009}, pages = {CR211-CR216}, keywords = {retina, atherosclerosis, progesterone, estradiol, dehydroepiandrosterone sulfate}, journal = {Medical science monitor}, volume = {15}, number = {5}, issn = {1234-1010}, title = {Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men}, keyword = {retina, atherosclerosis, progesterone, estradiol, dehydroepiandrosterone sulfate} }
@article{article, year = {2009}, pages = {CR211-CR216}, keywords = {retina, atherosclerosis, progesterone, estradiol, dehydroepiandrosterone sulfate}, journal = {Medical science monitor}, volume = {15}, number = {5}, issn = {1234-1010}, title = {Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men}, keyword = {retina, atherosclerosis, progesterone, estradiol, dehydroepiandrosterone sulfate} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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