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Improvement of Biocompabitility of a Biomedical-grade Stainless Steel 316LVM Surface by Electrochemical Passivation and Nanostructuring

An electrochemical technique was used to modify a biomedical-grade 316LVM stainless steel surface in order to improve its biocompatibility. A significant improvement in general and pitting corrosion resistance of 316LVM was achieved ; 97% protection efficiency against general corrosion, and 100% efficiency against pitting corrosion in physiological solutions. A significant improvement in cell/surface interactions was achieved. The electrochemically treated surface also demonstrated a significantly lower thrombogenicity. A change in dielectric properties of the passive film and its increase in thickness were found to be the major factors responsible for the observed improvement in the corrosion resistance, while the cell/surface interactions were controlled by surface topography, physico-chemical properties, and kinetics, surface concentration and conformation of adsorbed fibronectin.

316LVM stainless steel; passivation; corrosion; cell / surface interactions; biocompatibility

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