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Double immunoenzymatic APAAP staining for the detection of leukemia-associated immunophenotypes

Detection of unusual or aberrant cell immunophenotype with flow cytometry is the basis for the immunologic recognition of minimal residual disease (MRD) in patients with acute leukemia (AL. Resullts of this study indicate that double APAAP staining can identify leukemic cells in samples with a cytomorphologic pattern consistent with remission, but its applicability in detection of MRD awaits additional studies on a larger number of patients.

acute leukemia ; leukemia associated immunophenotype ; immunocytochemistry

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