hrvatski

Djelovanje brzine aplikacije intraosealne anestezije na promjene krvnog tlaka i bila kod pasa: ogledna studija

Intraosseous anesthesia brings anesthetic solution in a spongious bone surrounding a tooth. Recent clinical researches in humans demonstrate that blood pressure and heart rate increase when intrassseous anesthesia was performed. Aim of this study was preclinical testing of prototype system for intraosseous anesthesia. Different speeds of application of anesthetic solution were compared for eventually change of blood pressure and heart rate in dogs. Four healthy males (correspond to ASA1 according to American Society of Anaesthiologists) were selected for pilot study, average weight 15.25&#177; 4.5kg. 1.4ml Lidocaine 2% with epinephrine 1:100.000 as vasoconstrictor was used for intraosseous anesthesia. General anesthesia was attained by IV injection of sodium pentobarbital 6% via the femoral vein. Single dose of 0.7ml of anesthetic solution was injected at different position in jaws for different rate: 40 seconds, 24 seconds, 12 seconds, and 6 seconds. Systolic, diastolic pressure and heart rate were measured before and after application. Results of pilot study in four male dogs shows that there is no statistical difference in systolic and diastolic blood pressure as the result of different time of application of anesthetic solution. There is statistical difference in heart rate before and after 24 seconds, as well as, before and after 40 second of application time (p<0.05). This study and evaluation of experiment procedure will be basis for further research.

intraosealna anestezija srcani ritam; krvni tlak; pas

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