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Pregled bibliografske jedinice broj: 404217

Reg IV protein and mRNA expression in different rat organs


Ažman, Josip; Starčević–Klasan, Gordana; Ivanac, Danijel; Picard, Anne; Jurišić–Eržen, Dubravka; Nikolić, Marina; Malnar, Daniela; Arbanas, Juraj; Jerković, Romana
Reg IV protein and mRNA expression in different rat organs // Acta Histochemica, 113 (2011), 8; 793-797 doi:10.1016/j.acthis.2010.11.008 (međunarodna recenzija, članak, znanstveni)


Naslov
Reg IV protein and mRNA expression in different rat organs

Autori
Ažman, Josip ; Starčević–Klasan, Gordana ; Ivanac, Danijel ; Picard, Anne ; Jurišić–Eržen, Dubravka ; Nikolić, Marina ; Malnar, Daniela ; Arbanas, Juraj ; Jerković, Romana

Izvornik
Acta Histochemica (0065-1281) 113 (2011), 8; 793-797

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Reg IV; Immunohistochemistry; Western blot; Gene expression; Rat
(Reg IV; immunohistochemistry; western blot; rat; gene expression; rat)

Sažetak
The Reg IV gene has been documented in the human colon, small intestine, stomach and pancreas. Expression of the Reg IV in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. Since the distribution of the Reg IV protein in normal rat tissue is unknown, the aim of this study was to reveal the expression of the Reg IV protein in structurally and functionally different rat organs. The expression of Reg IV gene was analyzed by Western blot and reverse transcription-polymerase chain reaction. Immunohistochemistry was used to localize Reg IV protein. Reg IV protein was expressed in pancreas, stomach, small intestine, colon, brain, spleen, kidney and urinary bladder in two-month-old rats. In addition, the expression of Reg IV mRNA by reverse transcription-polymerase chain reaction was confirmed. Our study provides detailed information about the expression and localization of Reg IV protein in different rat organs. These findings provide an evidence of Reg IV expression in different rat organs, which may help elucidate a potential role in growth and proliferation of different cells like other members of the Reg family genes which act as growth factors in the different organs.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
062-0620529-0517 - Regeneracija mozga, perifernog živca i skeletnog mišića u šećernoj bolesti (Romana Jerković, )

Ustanove
Medicinski fakultet, Rijeka

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • BIOSIS Previews (Biological Abstracts)
  • CAB Abstracts
  • EMBASE (Excerpta Medica)
  • MEDLINE


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