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Peroxidation and Age-Associated Diseases-Cause or Consequence?


Wildburger, Renate; Mrakovčić, Lidija; Štroser, Marina; Andrišić, Luka; Borović Šunjić, Suzana; Žarković, Kamelija; Žarković, Neven
Peroxidation and Age-Associated Diseases-Cause or Consequence? // Türkiye Klinikleri = Journal of Medical Sciences, 29 (2009), 1; 189-193 (međunarodna recenzija, pregledni rad, znanstveni)


Naslov
Peroxidation and Age-Associated Diseases-Cause or Consequence?

Autori
Wildburger, Renate ; Mrakovčić, Lidija ; Štroser, Marina ; Andrišić, Luka ; Borović Šunjić, Suzana ; Žarković, Kamelija ; Žarković, Neven

Izvornik
Türkiye Klinikleri = Journal of Medical Sciences (1300-0292) 29 (2009), 1; 189-193

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Aging ; oxidative stress ; lipid peroxidation ; 4-hydroxynonenal

Sažetak
Aging is progressive and deleterious process in many aspects common to all living organisms. In humans, development of various diseases, such as neurodegenerative diseases, cardiovascular diseases, some forms of cancer, metabolic disorders, diabetes, certain autoimmune and bone diseases, is proportional to aging. Therefore, it seems that excess in production of reactive oxygen species causing oxidative stress and lipid peroxidation plays important role in aging, homeostasis and initiation of age-associated diseases. Hence, oxidative stress and lipid peroxidation could be considered both as causative for particular age-associated diseases as well as cofactors of aging. However, constant but moderate oxidative stress might have beneficial impact upon increment of antioxidative capacities thus preventing initiation of age-associated diseases and extending aging.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-0982464-2519 - Lipidi, slobodni radikali i njihovi glasnici u integrativnoj onkologiji (Neven Žarković, )
108-0000000-0028 - Oksidacijski stres i tumori središnjeg živčanog sustava (Kamelija Žarković, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus