engleski

Optimization procedure to detect high-affinity ligand-receptor amino acid pairs

We describe the procedure for detecting the most probable ligand-receptor amino acid pairs. The method is suitable for investigating epitope-paratope interactions. The procedure is based on the combination of methods from the Molecular Recognition Theory and algorithms for the prediction of protein secondary structure. The results are tested on the molecular models of CD20, PSA, α -melanotropin and Newcastle virus surface proteins.

molecular ; recognition ; CD20 ; PSA ; alpha-melanotropin ; Newcastle virus ; surface ; proteins

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