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Pregled bibliografske jedinice broj: 400285

Adherence to the Mediterranean diet is associated with a lower risk of body-shape changes in Croatian patients treated with combination antiretroviral therapy


Turčinov, Drago; Stanley, C.; Rutherford, G.W.; Novotny, T.E.; Begovac, Josip
Adherence to the Mediterranean diet is associated with a lower risk of body-shape changes in Croatian patients treated with combination antiretroviral therapy // European journal of epidemiology, 24 (2009), 5; 267-274 doi:10.1007/s10654-009-9330-2 (međunarodna recenzija, članak, znanstveni)


Naslov
Adherence to the Mediterranean diet is associated with a lower risk of body-shape changes in Croatian patients treated with combination antiretroviral therapy

Autori
Turčinov, Drago ; Stanley, C. ; Rutherford, G.W. ; Novotny, T.E. ; Begovac, Josip

Izvornik
European journal of epidemiology (0393-2990) 24 (2009), 5; 267-274

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Antiretrovirals; HIV; lipoatrophy; lipohypertrophy; Mediterranean diet

Sažetak
Lipoatrophy and lipohypertrophy have been observed during long-term combination antiretroviral therapy (CART). We investigated whether consumption of a Mediterranean diet is associated with lower risk of body-shape changes in Croatian patients treated with CART. Between May 2004 and June 2005, we conducted a cross-sectional study of 136 adults with HIV-1 infection who were treated with CART for at least 1 year. Lipoatrophy and lipohypertrophy were assessed by self-report and physical examination. Adherence to a Mediterranean diet was determined by a 150-item questionnaire ; a 0-9 point diet scale was created that stratified respondents as having low adherence (<4 points) and moderate to high adherence (&#8805; 4 points). Lipoatrophy was present in 41% and lipohypertrophy in 32% of participants. Non-smokers with a dietary score &#8805; 4 had the lowest risk for lipoatrophy. Stavudine use, female gender, and duration of CART were also independently associated with a higher risk of lipoatrophy. A dietary score of &#8805; 4 was associated with lower risk of lipohypertrophy (adjusted OR 0.3, 95% CI 0.1-0.7 ; P = 0.012). Female gender, longer duration of CART, and longer known duration of HIV infection prior to CART were also independently associated with higher risk of lipohypertrophy. In conclusion, Croatians who did not smoke and moderately or highly adhered to the Mediterranean diet were least likely to have the clinical syndrome of lipoatrophy. Moderate to high adherence to a Mediterranean diet was associated with a lower risk of lipohypertrophy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1080116-0098 - Epidemiološka i klinička obilježja zaraze HIV-om u Hrvatskoj (Josip Begovac, )

Ustanove
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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