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Pregled bibliografske jedinice broj: 397890

Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study


Supek, Selma; Josef Golubić, Sanja; Bryant, Jennifer; Donahue, Chris; Montaño, Rebecca; Adair, John; Hart, Blaine; Knoefel, Janice; Stephen, Julia; Aine, Cheryl
Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study // Proceedings of the 16th International Conference on Biomagnetism (BIOMAG 2008) / Kakigi, K ; Yokosawa, K ; Kuriki, S. (ur.).
Sapporo: Hokkaido University Press, 2008. str. 171-173 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)


CROSBI ID: 397890 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study

Autori
Supek, Selma ; Josef Golubić, Sanja ; Bryant, Jennifer ; Donahue, Chris ; Montaño, Rebecca ; Adair, John ; Hart, Blaine ; Knoefel, Janice ; Stephen, Julia ; Aine, Cheryl

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings of the 16th International Conference on Biomagnetism (BIOMAG 2008) / Kakigi, K ; Yokosawa, K ; Kuriki, S. - Sapporo : Hokkaido University Press, 2008, 171-173

ISBN
978-4-8329-0355-5

Skup
International Conference on Biomagnetism (16 ; 2008)

Mjesto i datum
Sapporo, Japan, 25.-29.08.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
MEG; auditory add ball paradigm; cortical neurodynamics; aging; MCI; AD

Sažetak
Neuromagnetic source localization was conducted on data obtained from an auditory oddball task to examine alterations in cortical neurodynamics, particularly in medial temporal lobes (MTL), of patients diagnosed as MCI and AD relative to age-matched healthy elderly. MEG data were recorded with a CTF 275-channel whole-head system in a magnetically shielded room at the MIND Institute. The auditory oddball task consisted of 400 frequent (1.000 Hz, p=0.8) and 100 rare (1.200 Hz, p=0.2) binaurally presented tones. Calibrated Start Spatio-Temporal (CSST) modeling, launched from within MRVIEW, was used for source localization and cortical temporal dynamics estimation. Differences noted in the cortical activation patterns were: 1) early unilateral MTL activation to rare stimuli in AD compared to bilateral activation in healthy elderly and MCI and 2) reduced and/or altered late MTL activity for both rare and frequent stimuli in MCI and AD patients relative to healthy elderly. Both findings suggest that MTL activity patterns may provide important information for discriminating between participant diagnostic categories.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
119-1081870-1252 - Kognitivna neurodinamika (Supek, Selma, MZOS ) ( POIROT)

Ustanove:
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Selma Supek (autor)

Avatar Url Sanja Josef Golubić (autor)


Citiraj ovu publikaciju

Supek, Selma; Josef Golubić, Sanja; Bryant, Jennifer; Donahue, Chris; Montaño, Rebecca; Adair, John; Hart, Blaine; Knoefel, Janice; Stephen, Julia; Aine, Cheryl
Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study // Proceedings of the 16th International Conference on Biomagnetism (BIOMAG 2008) / Kakigi, K ; Yokosawa, K ; Kuriki, S. (ur.).
Sapporo: Hokkaido University Press, 2008. str. 171-173 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
Supek, S., Josef Golubić, S., Bryant, J., Donahue, C., Montaño, R., Adair, J., Hart, B., Knoefel, J., Stephen, J. & Aine, C. (2008) Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study. U: Kakigi, K., Yokosawa, K. & Kuriki, S. (ur.)Proceedings of the 16th International Conference on Biomagnetism (BIOMAG 2008).
@article{article, year = {2008}, pages = {171-173}, keywords = {MEG, auditory add ball paradigm, cortical neurodynamics, aging, MCI, AD}, isbn = {978-4-8329-0355-5}, title = {Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study}, keyword = {MEG, auditory add ball paradigm, cortical neurodynamics, aging, MCI, AD}, publisher = {Hokkaido University Press}, publisherplace = {Sapporo, Japan} }
@article{article, year = {2008}, pages = {171-173}, keywords = {MEG, auditory add ball paradigm, cortical neurodynamics, aging, MCI, AD}, isbn = {978-4-8329-0355-5}, title = {Neuromagnetic auditory activity reflects differences between normal aging, MCI and AD subjects: An oddball study}, keyword = {MEG, auditory add ball paradigm, cortical neurodynamics, aging, MCI, AD}, publisher = {Hokkaido University Press}, publisherplace = {Sapporo, Japan} }




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