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izvor podataka: crosbi

Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA (CROSBI ID 150289)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Rusak, Gordana ; Piantanida, Ivo ; Bretschneider, Sabine, Ludwig-Müller, Jutta Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA // Journal of inorganic biochemistry, 103 (2009), 12; 1597-1601. doi: 10.1016/j.jinorgbio.2009.08.008

Podaci o odgovornosti

Rusak, Gordana ; Piantanida, Ivo ; Bretschneider, Sabine, Ludwig-Müller, Jutta

engleski

Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA

Due to broad spectrum of biological activities of flavonoids, their target molecules in the cell are intensively studied. We examined the interactions of flavonoid quercetin (Q) and its lanthanum complex (QLa3+) with plant viral satellite (sat) dsRNA. Comparison of the cumulative binding and the estimated intercalative binding constant pointed towards an additional binding mode of quercetin to exclusively viral dsRNA, which is not recorded for synthetic dsRNAs. The QLa3+ showed significantly higher affinity toward viral dsRNA than Q and La3+ alone, most likely as the consequence of quercetin intercalation accompanied by additional electrostatic interaction of La3+ with the negatively charged viral RNA backbone.

Flavonoids ; Rare Earth Metals ; Cucumber Mosaic Virus ; Nucleic Acids

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Podaci o izdanju

103 (12)

2009.

1597-1601

objavljeno

0162-0134

10.1016/j.jinorgbio.2009.08.008

Povezanost rada

Kemija, Biologija

Poveznice
Indeksiranost