3,7-dichloro-2,6-di-(4,4'-butylamidino)benzo(2,1-b : 4,5-b')dithiophene dihydrochloride as potential anti-HIV agent (CROSBI ID 473118)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Pavličić, Dubravka ; Karminski-Zamola, Grace
engleski
3,7-dichloro-2,6-di-(4,4'-butylamidino)benzo(2,1-b : 4,5-b')dithiophene dihydrochloride as potential anti-HIV agent
A lot of scientific papers which appeared in the last ten years, describe the synthesis and antiviral activity against HIV and HIV-opportunistic deseases of the bis-amidinosubstituted heteroczclic compounds. This data prompted us to synthesize 3,7-dichloro-2,6-di-(4,4'-butylamidino)benzo(2,1-b : 4,5-b')dithiophene dihydrochloride as potential anti-HIV agent. It could serve as intercalator, which could bind on the DNA of the HIV-virus.The compound in title was synthesized in multistep synthesis starting from corresponding chloride over n-butyldiamide and diimidochloride.
3;7-dichloro-2;6-di-(4;4'-butylamidino)benzo(2;1-b : 4;5-b')dithiophene dihyd; anti-HIV agentrochloride
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Podaci o prilogu
A-63, 115-x.
2000.
objavljeno
Podaci o matičnoj publikaciji
XIXth European Colloquium on Heterocyclic Chemistry, Book of Abstracts
Aveiro:
Podaci o skupu
XIXth European Colloquium on Heterocyclic Chemistry
poster
19.07.2000-22.07.2000
Aveiro, Portugal