Antitumor activity of new heteropolycyclic substances from the series of benzo-thieno-quinolones and thieno-thienyl-quinolones (CROSBI ID 473117)
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Podaci o odgovornosti
Slade, Neda ; Grdiša, Mira ; Dogan-Koružnjak, Jasna ; Karminski-Zamola, Grace ; Zamola, Branimir ; Pavelić, Krešimir
engleski
Antitumor activity of new heteropolycyclic substances from the series of benzo-thieno-quinolones and thieno-thienyl-quinolones
A few new condensed heterocyclic quinolones from benzo(b)thieno- and thieno(2, 3-b)thienyl- series were prepared by multistep and photochemical synthesis, with specific substituents in benzene and thiophene nucleus as well as in the quinolone nucleus. All compounds were tested in vitro for their cytoststic activities on human fibroblast cell line WI-38 and on the following malignant human tumor cell lines: cervical carcinoma(HeLa). breast carcinoma(MCF-7), colon carcinoma (CaCo-2), pancreatic carcinoma(MIA PaCa-2), laryngeal carcinoma(Hep-2) and melanoma(HBL).
Antitumor activity; benzothieno- dithienoquinolones
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
115-115-x.
2000.
objavljeno
Podaci o matičnoj publikaciji
2nd International Conference on Signal Transduction ICST, Program and Abstracts
Zagreb:
Podaci o skupu
2nd International Conference on Signal Transduction ICST
poster
26.05.2000-31.05.2000
Cavtat, Hrvatska