engleski

Stimulation by levamisole of cell-mediated immunity in weaned pigs

Commercial crossbred pigs weaned at four weeks were allocated into three equal groups. The experimental group 1 was intramuscularly, and the experimental group 2 was per os, primed with levamisole at an immunostimulatory dose of 2.5 mg/kg once daily, for three consecutive days, and controls received saline. Venous blood samples from all pigs were collected after the last levamisole or saline dose was given (day 0), and 35 days later (day 35) for flow cytometry analysis. The results obtained by immunophenotyping of isolated circulating lymphocytes on day 35 indicate that priming by levamisole of weaned pigs selectively recruited CD4+, CD8+ and CD4+CD8+, but not CD21+ cells in the systemic circulation.

Weaned pigs ; Levamisole ; Immunomodulation ; Cell-mediated immunity

Proceedings of the 17th International Symposium Animal Science Day ” Priorities for the European animal production in a global market ”, Session 1: Animal Breeding, Conservation and Biotechnology, Abano Terme, Padova, Italija, 15.9.-18.9.2009.