engleski

Folliculitis decalvans u 16-godišnjaka nakon emocionalnoga stresa

The authors report the case of fast progressive folliculitis decalvans, which developed in a 16-year old patient two weeks after he experienced a strong emotional stress. The family history revealed folliculitis decalvans in the patient´s uncle. The diagnosis was based on clinical signs, result of bacterial culture and histology. Routine laboratory investigation were normal, but patient had significantly number of CD3+ and CD4+ cells, increased proportion and number of CD8+ and CD16+ cells, low IgA value and impaired lymphocyte stimulation with phytohemaglutinin and concanavalin A. The patient was also evaluated for indicators of stress. Objective physical indicators of stress were measured by bihevioral observation and medical examination and subjective indicators by eight-item symptom checklist. Testing revealed numerous stress indicators, anxiety and stress perception level was high. A possible explanations for the infection progressing to hair loss in the patient could lie in impaired cell-mediated immunity. The autors discussed the possible role of psychoneuroimmunological and genetic mechanisms in the pathogenesis of folliculitis decalvans.

folliculitis decalvans; genetics; psychoneuroimmunology

nije evidentirano