engleski

Influence of blood pressure and hypertension on proximal tubular damage should be considered in Endemic (Balkan) Nephrppathy

Proximal tubular damage is an early sign of renal impairement in endemic (Balkan) nephropathy (EN), and low molwcular proteiuria is hallmark of it. Detremination of alpha 1 microglobulinuria (AF1) and albuminuria are essential parts in diagnostic algoritm that is currently reevaluated. However, hypertension is not only related to microalbuminuria but also to increased urinary excretion of alfa 1 microglobulin and microalbuminuria in EN were analized in 754 inhabitans of theee Croatian endemic villages and control village of Klakar.

Endemic nephropathy; blood pressure; alfa 1 microglobulin

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