engleski

Evaluation of the Antitrypanosoma cruzi Activity of three Synthetic DNA Binders

Trypanosoma cruzi shows a complex life cycle, characterized by several forms both in the insect vector and in mammalian host. The therapy against this infection relies mainly on two therapeutic drugs, with low efficiency and undesirable side effects. Due to these facts the search of new leader compounds with trypanocidal activity is considered as a relevant goal. In the present work we studied three synthetic DNA binders

Trypanosoma cruzi; Chagas' disease; benzimidazoles; amidines

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